Cytiva HiScreen™ Capto™ Core 400, Multimodal Columns

For intermediate purification and polishing of viruses and other large biomolecules (Mr > 350,000) in flowthrough mode. An excellent alternative to size-exclusion chromatography (SEC) resins that are typically employed in the final stages of virus purification in vaccine manufacture

• Offers dual functionality, size exclusion, and binding chromatography
• Novel core bead technology allows efficient capture of contaminants, while target molecule is collected in the flowthrough
• Convenient small-scale purification, process development, and scale-up
• Straightforward optimization due to flowthrough chromatography and robust performance
• Significantly improved productivity and higher flow rates compared with gel filtration methods